The Haglund Research Group
Department of Chemistry
Publications
2024
Exploring the folding landscape of leptin: Insights into threading pathways
FB da Silva, JM Simien, RG Viegas, E Haglund, VBP Leite
Journal of Structural Biology 216 (1), 108054
Biophysical characterization of the CXC chemokine receptor 2 ligands
P Martin, EA Kurth, D Budean, N Momplaisir, E Qu, JM Simien, ...
Plos one 19 (4), e0298418
GE Orellana, E Haglund
American Chemical Society
2023
JK Noel, E Haglund
The Journal of Physical Chemistry B 128 (1), 117-124
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The Biological Implications of Threaded Protein Topologies
E Haglund
JSciMed Central 8 (2), 1081
A Small Contribution to a Large System: The Leptin Receptor Complex
JM Simien, GE Orellana, HTN Phan, Y Hu, EA Kurth, C Ruf, F Kricek, Q Wang, AV Smrcka, and E Haglund
Journal of Physical Chemistry B 127 (11), 2457−2465
2021
2020
J Danielsson, JK Noel, JM Simien, BM Duggan, M Oliveberg, JN Onuchic, ...
Journal of Molecular Biology 432 (9), 3050-3063
Pierced-Lasso Topology Discovery
2018
Uncovering the molecular mechanisms behind disease-associated leptin variants
E Haglund, L Nguyen, NP Schafer, H Lammert, PA Jennings, JN Onuchic
Journal of Biological Chemistry 293 (33), 12919-12933
2017
Pierced lasso topology controls function in leptin
E Haglund, A Pilko, R Wollman, PA Jennings, JN Onuchic
The Journal of Physical Chemistry B 121 (4), 706-718
152017
2015
Engineering covalent loops in proteins can serve as an on/off switch to regulate threaded topologies
E Haglund
Journal of Physics: Condensed Matter 27 (35), 354107
2014
Pierced lasso bundles are a new class of knot-like motifs
E Haglund, JI Sulkowska, JK Noel, H Lammert, JN Onuchic, PA Jennings
PLoS computational biology 10 (6), e1003613
2012
The unique cysteine knot regulates the pleotropic hormone leptin
E Haglund, JI Sułkowska, Z He, GS Feng, PA Jennings, JN Onuchic
Public Library of Science 7 (9), e45654
Other Publications
2015
H Lammert, JK Noel, E Haglund, A Schug, JN Onuchic
The Journal of Chemical Physics 143 (24), 243141
KM Fisher, E Haglund, JK Noel, KL Hailey, JN Onuchic, PA Jennings
PLoS One 10 (12), e0144067
2012
Trimming down a protein structure to its bare foldons: spatial organization of the cooperative unit
E Haglund, J Danielsson, S Kadhirvel, MO Lindberg, DT Logan, M Oliveberg
PLoS One. 2012;7(9):e45654. doi: 10.1371/journal.pone.0045654